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The activation of the Nrf2 (nuclear factor erythroid-derived 2)/ARE (antioxidant response elements) pathway is likely a principal and underlying mechanism of hormesis, which can limit age-related damage, numerous disease processes progression, and induction of toxicities due to chemicals and radiations ( 6 Synergic anticancer effect of sulforaphane in combination with other chemotherapeutic agents Sulforaphane can also be used with conventional cancer treatments to achieve an enhanced effect

DSIP is recognized for its role in regulating sleep and may also impact activity in the cerebral cortex

Water molecules were modelled manually into clear spherical density within reasonable hydrogen bonding distance to amino-acids or other waters

Nagaya, M